However, many people with fatty liver have other risk factorssuch as metformin use, proton pump inhibitors, or dietary restrictionsthat can independently lead to B12 deficiency, making monitoring important when symptoms or risk factors are present
Medical Conditions, Surgeries, and Medications Lack of intrinsic factor (a protein made in the stomach thats needed for B12 absorption) - this condition is called pernicious anemia Thyroid disease HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome) Autoimmune diseases like type 1 diabetes, where the immune system in the body attacks its own tissues Gastric bypass surgery (weight loss surgery) Chronic gastritis surgery Certain medications like heartburn drugs (proton pump inhibitors) which reduce stomach acid production Who Is At Risk of Vitamin B12 Deficiency
Rare hypersensitivity reactions , including cobalt allergy (as cobalamin contains cobalt), have been documented
Without baseline biomarker assessmentsuch as serum B12, homocysteine, or liver function markersit is difficult to determine whether deficiency in any component is limiting your metabolic capacity or whether supplementation will meaningfully improve outcomes
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Vitamin B-12 is an essential nutrient that plays a vital role in the functioning of the human body