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TCGA data analysis The cBioportal for Cancer Genomics (www.cbioportal.org) was used to analyse the relationship between p53 protein expression and SLC7A11 or NQO1 mRNA expression across all available RPPA and RNAseq datasets

When evaluating alternative definitions, AH rates similarly rose rapidly, peaking 2020-2021, and then appeared to plateau (Definition #2:426 to 1,024 per 100,000-py (2010 to 2021), plateaued to 910 per 100,000-py in 2023

The 3 H-inositol is taken up by the cells and incorporated into IP 3

Immunocytochemistry Astrocytes on coverslips were fixed in 4% paraformaldehyde (FUJIFILM Wako) for 15 min at room temperature

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Immune Support Robust cellular immunity relies entirely on adequate intracellular antioxidant reserves