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10.1016/S0140-6736(18)30475-6 45

Rosa Neto JC, Lira FS, Oyama LM, Zanchi NE, Yamashita AS, Batista Jr ML, et al

5-Amino-1MQ inhibits the enzyme NNMT (nicotinamide N-methyltransferase), which preserves intracellular NAD+ and activates AMPK-dependent mitochondrial fat oxidation

doi: 10.4049/jimmunol.0903595 62 PisitkunPHaH-LWangHClaudioETivyCCZhouHet al

Studies have indicated that the increase of the autophagy level in vivo can lead to the degradation of ferritin and the increase of iron level, thus leading to oxidative damage of cells through the Fenton reaction [66, 67]

I landed on an old world black and white encaustic pattern tile from Della Torre, an Italian company, that feels very classic and simplistic- pictured below