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Holt JAG

doi: 10.3390/nu16162810

Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection

Finally, we propose a conceptual model illustrating how bilirubin serves as a central homeostatic mediator integrating multiple neuroprotective pathways

Erastin, a representative xCT inhibitor, binds to xCT directly, thereby inhibiting cystine uptake and lowering intracellular GSH levels via downstream pathways