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Although obicetrapib increased HDL-C levels as anticipated by its mechanism of action, it remains unclear whether this translates into clinical benefit, as prior CETP inhibitor trials have demonstrated that HDL-C elevation alone does not necessarily reduce cardiovascular events

Interestingly, the location of neutrophils and macrophages coincided with the loss of alpha smooth muscle actin (aSMA) signal within the tunica media, indicating enhanced SMC loss at the site of inflammatory cell infiltration

Transient congenital hypothyroidism caused by biallelic mutations of the dual oxidase 2 gene in Japanese patients detected by a neonatal screening program

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5 mg vial reconstituted with 2.5 ml BAC water = 0.02 mg per unit