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Rifampicin can Induce Antibiotic Tolerance in Mycobacteria Via Paradoxical Changes in Rpob Transcription

J., Yamamura, Y., Kobayashi, T., Wang, M., Yoritaka, A., Minoshima, S., Shimizu, N., & Mizuno, Y

Nov 12, 2024 Dulce Minaya , Sitara Cullinan , and colleagues (including alumni Sammi Kim and Neil Maclang ) have a paper recently published in Gut Microbes

This effect was reversed by deletion of NOX1-4, NOX3 alone, or treatment with the ROS scavenger N-acetyl cysteine (NAC)

This trial aimed to assess ACs potential to prevent proteinuria relapse or achieve remission, slow the decline of renal function, and reduce hematuria (ClinicalTrials.gov Identifier: NCT02662283)

Weve already encountered superoxide dismutase 2 (SOD2), which converts the superoxide anion into hydrogen peroxide