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According to Kannt & Pfenninger in Frontiers in Physiology , NAD is a critical coenzyme in mitochondrial energy metabolism, and strategies that preserve NAD have wide-ranging effects on health and performance (Kannt & Pfenninger, Frontiers in Physiology )

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Intramuscular Injection The B12 is injected into the muscle using a fine needle

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Cycle breaks become mandatory if you have been on protocol for 12+ weeks continuously or if response has dropped significantly despite dose adjustment