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In the CY 2025 PFS proposed rule (89 FR 62034 through 62035), we proposed to adopt minimum criteria for a qualifying data submission for the Promoting Interoperability performance category submission to include all of the required reporting elements for the category, including data on all required measures (including any claim of an applicable exclusion), required attestation statements, the CEHRT ID, and the start and end date for the applicable performance period

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The metabolism and elimination of NAD+ (and its by-products) could be altered in advanced hepatic or renal dysfunction, and high-dose NAD+ might theoretically affect cardiovascular dynamics, so practitioners generally avoid or closely supervise NAD+ use in such settings