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Research overwhelmingly describes the safety of GHK-Cu positively, such as when the authors of a 2018 review called it a safe, inexpensive, extensively studied compound.14 However, even though copper peptides have demonstrated an impressive safety track record in studies, there are (as with most skin care actives) a few safety risks to consider

The contrast in their results is the single most important piece of evidence in the at-home copper peptide conversation, and almost no consumer-facing article cites it

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1) Hydration & Electrolytes Even mild dehydration raises perceived effort, slows recovery, and can trigger headaches that knock you off schedule