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Description

10.1289/ehp.97105s4907 281

208 This represents one of the rare examples of mTORC1s nuclear activity

The samples were incubated with primary antibodies overnight at 4 C in blocking solution

16 Ivacaftor stabilizes the open state of CFTR, thus increasing chloride transport of wild-type CFTR and stimulates the activity of G551D-CFTR to 50% of that of non-mutated CFTR