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54 HuangX.ChengZ.SuQ.ZhuX.WangQ.ChenR.et al (2012)

(c) binding of drug to a cell surface receptor that is then internalized

Implementing such innovative pre- and rehabilitation strategies may lead to a full recovery, sustainable health conditions and, therefore, facilitating patients comeback to normal daily activities, family and professional life

Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Tirzepatide was engineered by modifying the native GIP peptide sequence with a fatty acid chain that extends its half-life to approximately five days, making once-weekly dosing possible

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