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Deficiency is particularly common in elderly people because the ability to absorb vitamin B12 can decrease with age

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It performs three basic functions: Reduces appetite by signalling satiety to the brain and suppressing cravings Slows down digestion and delays gastric emptying to make you feel fuller for longer Stimulates insulin secretion and suppresses glucagon release Collectively, this helps with blood sugar control and maintaining a healthy weight

Moreover, the plasticity and context-dependency of microglial states pose an inherent challenge

The deleterious effects of this accumulation of lipids is termed lipotoxicity

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