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In vitro GSH sensitivity and selectivity experiments The HT adducts were prepared by combining the HT protein (50 M in PBS) with the respective TRaQ-G ligand (1.52x excess, stock solution 50 mM in DMSO) and rotating the resulting solution for 1 h at 20 C

Free Radical Research, 51 (4), 428438

7.4 Synergistic intervention 7.4.1 Combination of Nrf2 activators and A clearance Nrf2 activators centered on sulforaphane are driving a paradigm shift in AD treatment from traditional single-pathway approaches toward a dual-track strategy targeting both pathological clearance and ferroptosis blockade

The total GSH content is calculated as twice the GSSG concentration of the sample, without the removal of GSH

doi: 10.1038/s41392-024-01772-w 168 GuoQMaMYuHHanYZhangD

The psychology of the peptide space is also worth noting, as it ties into how wellness and body optimization can be gendered