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For endurance athletes, this can be distinctly disadvantageous: accelerated glycogen depletion may precipitate earlier fatigue and reduce sustained performance within a single session, particularly before any long-term adaptations can occur

We propose a combined therapeutic strategy of immunomodulators + metabolic inhibitors + microbiota intervention, moving beyond traditional single-factor research paradigms to establish a multi-omics integrated framework for the precise treatment of CMspanning molecular mechanisms to clinical translationand propelling the field of neuroinfectious diseases towards a host-pathogen-microenvironment systemic regulation paradigm

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The AESs used for the construction of H37Rv metE ::Kan R and metH ::Kan R mutants were also electroporated in the M

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Metab Brain Dis 31:593599 Liu X, Cao S, Zhang X (2015) Modulation of gut microbiotabrain axis by probiotics, prebiotics, and diet