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Its main active ingredient, polysaccharides (GLPs), treats complications including nephropathy, liver injury, cardiomyopathy, neuropathy, retinopathy, and erectile dysfunction due to diabetes through multi-target pathways, including improving glucose and lipid metabolism (Jones, 2016), regulating oxidative stress (Yamada et al., 2020), inhibiting cell apoptosis (Xia et al., 2021), repairing islet cells (Li et al., 2017), alleviating inflammatory responses (Wang L

(B) Photographs show phase-contrast images of PEMs at the indicated time points in the time lapse movie shown in (A)

Berberine also reduces apoptosis by modulating the PI3K/Akt and p38-MAPK pathways (Han et al., 2023)

Retatrutide is a triple hormone receptor agonist that targets GLP-1, GIP, and glucagon receptors

Therefore, the Working Group judged this study to be inadequate for the evaluation of the carcinogenicity of aspartame in experimental animals.] 3.1.2

Half of it was baseless or wrong