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Anticholinesterases, such as Mestinon (pyridostigmine bromide), are often used as a first-line treatment for MG

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Furthermore, the rate of BIA increased throughout disease progression

Stable cell lines were generated via selection with 2 g/mL puromycin (Gibco, A1113803, USA) for 7 days and validated by reverse transcription quantitative PCR (RT-qPCR)

Consistently, they also observed increased expression of apoptotic proteins and decreased TRPM7 levels in the samples obtained from the SNpc region of human Parkinsons disease patients (Sun et al., 2020b)