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This induces the degradation of HMGCR and squalene monooxygenase, maintaining intracellular cholesterol homeostasis by inhibiting cholesterol biosynthesis

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In cells treated with 5% CSE for 8 h, we found fainter and less pronounced staining of mitochondria, which confirmed mitochondrial depolarization detected by flow cytometry (Fig

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Careful interpretation of results is important, since passive exposure to cigarette smoke can result in significant accumulation of nicotine, followed by the appearance of its metabolites in various body fluids

Thanks to this training, we now know why smoking is a public health issue targeting low-income communities of color