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Microbiol (Reading England) (2003) 149(Pt 3):66572

You want localized, sustained dermal concentration, not a plasma spike that clears before fibroblasts finish one cell cycle

Oxidative damage triggers the DNA damage response, which subsequently leads to a decrease in MAD2 expression and its improper localization through Chk1, resulting in aneuploidy in murine oocytes

These mechanistic insights position microbial metabolite modulation as a promising therapeutic strategy for allergic asthma and related airway pathologies, bridging microbial ecology with clinical immunology through targeted microbiome engineering approaches

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The SVZ may therefore be an interesting target reservoir for treatments designed to promote myelin repair in elderly patients