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Additionally, high expression rate of nuclear NF-B p65 in FISS and dose-dependent inhibitory effects on the growth of FISS primary cells treated with NF-B inhibitors suggested a role of NF-B in FISS development (Hsueh et al., 2019)

Potential Applications Based on the preclinical research, several potential applications have been proposed, though it's crucial to understand that "proposed" does not equal "proven." These represent areas where researchers have observed BPC-157 activity in laboratory settings: Gastrointestinal Healing and Barrier Function Given BPC-157's origin in gastric secretions, much research has focused on its potential effects on the gastrointestinal tract

Neuroprotection Against Parkinsons Models MPTP selectively destroys nigrostriatal dopaminergic neurons, producing tremor, rigidity, akinesia, and catalepsy in rodents