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The accumulation of amyloid plaques is a pivotal factor associated with subsequent neuronal toxicity in AD pathogenesis, eventually associated with synaptic dysfunction and more severe cognitive deficits [38]

Discussions around the compound also touch on possible anti-inflammatory effects and areas like neuroprotection or antimicrobial activity, although these topics remain part of ongoing research

The pathological cascade of SCIRI involves the synergistic effect of multi-dimensional pathological mechanisms

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2.5 Weighted gene co-expression network analysis The R package weighted gene co-expression network analysis (WGCNA) was used to identify the network of genes from the transcriptome data and seven physiological indices

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