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Although this approach has promising results in infection neutralization, large-scale creation of monoclonal antibodies is costly, labor intensive, and time-consuming, especially against emerging pathogens

However, in all 4 patient samples, S -cysteinylation was detected not only at Cys34 but also at other cysteine residues, Cys101 and Cys392, that form an intramolecular disulfide bond in native HSA

In addition, quantitative measurements of the intestinal villus width [(villus apical width + villus basal width)/2], villus height (from the tip to base), and villus surface area [(villus apical width + villus basal width)/2 villus height] were determined in 10 complete, full-sized villi not showing any bending, mechanical damage, or fixation and/or processing artifacts following the guides of Wilson et al

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Hence, the validation of the physiological relevance of the detected interactions remains a major challenge

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