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doi: 10.1186/s13041-020-00715-0 [DOI] [PMC free article] [PubMed] [Google Scholar] 130

Meller J, Vidali L, Schwartz MA (2008) Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration

Granulysin is a cytotoxic mediator involved in keratinocyte death and is highly expressed in SJS/TEN blister fluid and serum [31, 73, 74]

Neutrophil cytosolic factor 1 (NCF1) is a significant genetic factor linked to autoimmune disorders, and NOX2-derived ROS are observed specifically in the mutated NCF1 gene, contributing to the malfunctioning of NCF1 in lupus

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This review aims to provide a comprehensive overview of the genetic and regulatory pathways driving antibiotic resistance in UPEC, offering insights that may guide the development of effective treatment strategies and help mitigate the ongoing spread of antimicrobial resistance