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Read more When More Skincare Becomes Too Much What Happens When an Ingredient Is Over-Dosed One of the most common assumptions in skincare is simple:If an ingredient works, more of it must work better. But in formulation, that

Am J Physiol Regul Integr Comp Physiol (2007) 293:R161929

Wang, H., Wang, H., Gao, C., & Liu, L

These verdicts characterize the regulation of sortilin shedding and identify a novel mechanism by which sortilin ectodomain shedding acts as a regulatory switch for delivery of BDNF to the secretory pathway or to the lysosome, thus modulating the bioavailability of endogenous BDNF (Fig

10.1261/rna.058180.116 32