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Patient-reported outcomes are positive in 70-85% of cases across published series, with the strongest effect in Fitzpatrick III-IV skin and the laxest dermis

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These studies underscored the therapeutic potential of combining glucose metabolism disruption with ferroptosis to achieve enhanced antitumor efficacy and prolonged survival.Disulfidptosis is a recently identified and distinct form of programmed cell death, characterized by the aberrant formation of disulfide bonds in actin cytoskeletal proteins, leading to cellular dysfunction and death [146]