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As expected, 0.1% BSA and 1% HSA reduced the potency of the lipidated peptides (elorilintide and cagrilintide) at human AMY1R, AMY3R, and CTR, while the non-lipidated rat amylin and sCT showed no significant potency shifts

Sustained retrograde signaling can lead to structural and functional remodeling of cardiac cells, affecting their growth, hypertrophy, and contractile function, as observed in conditions such as heart failure or hypertrophic cardiomyopathy 16,17

Students t tests were conducted to detect differences in metabolite concentrations between two phenotypes

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In general, for adults, a count lower than 4,000 white blood cells per microliter of blood is considered a low white blood cell count