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Since the concept of ferroptosis was proposed in 2012, the initial design ideas of some drugs like those listed in Table 1 were not based on the mechanism of ferroptosis

It supplies methyl groups to proteins

Consequently, achieving effective drug concentrations in the tumor becomes difficult and ultimately leads to drug resistance in breast cancer

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It is indicated for the treatment of anemia due to insufficient dietary intake of vitamin B12 in strict vegans for more than 4 years (diet without meat, dairy products, eggs or fish) and in this case it should be administered orally (drinkable ampoule)