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Source Data Extended Data Fig.5 (download XLSX Statistical source data

China has a high incidence rate of liver cancer [36], and viral infection [79], chronic alcoholism [50], eating moldy and deteriorate foods [116] can lead to hepatic cancer

The number of mice in each group is shown in Supplementary Table S1

it should only be accessed through legitimate clinical trials

GPX4 inhibition enhances glioma radiosensitivity by inducing oxidative stress-dependent SSG and degradation of transglutaminase 2 (TGM2), impairing DNA repair 126

The PD-L1/PD-1 interaction inhibits critical T cell signaling pathways (e.g., PI3K/AKT/mTOR), ultimately leading to exhaustion and apoptosis of the T cells, creating an immunosuppressive shield for tumors (88, 89)