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However, the presence of oxidatively damaged molecules could simply reflect secondary epiphenomena rather than having a causal role

1 Introduction Diseases of the retina are a primary factor in causing permanent blindness and vision loss, impacting millions of individuals globally (Hoon et al., 2014)

However, chronic inflammation itself is also a potent inducer of epigenetic memory that could explain the differences in epigenetic marking between resolved and sensitized USCs