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11.8% Avg Body Weight Loss* 68 Week Phase 3 Trial 1x Weekly Injection 2026 Expected FDA Decision Coming Soon A novel amylin analogue offering a different approach to weight management

3 Advances in understanding the gut-brain-kidney axis 3.1 Microbial metabolites and their impact Recent studies are increasingly demonstrating the influence of gut microbial-derived metabolites in the pathophysiology of the brain and kidneys