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at China Pharmaceutical University and Nanjing First Hospital: oral Dihexa restored spatial learning and memory in the APP/PS1 transgenic mouse model of Alzheimers disease via the PI3K/AKT signaling pathway, reduced neuroinflammation, and preserved hippocampal synaptophysin expression (Sun et al., Brain Sciences 2021)

As a key regulator of oxidative stress, Nrf2 governs the expression of ARE-dependent genes (62,125)

Therefore, we used TRAMPC1 (TrC1) prostate cancer cells overexpressing the clinically relevant AKT-variant AKT-E17K with increased AKT activity or wildtype AKT (AKT-WT) and analyzed the consequences of direct AKT inhibition (MK2206) and inhibition of AKT-dependent metabolic enzymes on the levels of cellular ROS, antioxidant capacity, metabolic state, short-term and long-term survival without and with irradiation

Cloning of phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an anti-apoptotic and growth promoting gene of Burkitt lymphoma cells

Emergency Pest Problems Need help with a wasp nest, scratching in the attic, mice in the basement, or sudden pest activity

The novel molecular mechanism of pulmonary fibrosis: Insight into lipid metabolism from reanalysis of single-cell RNA-seq databases