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Brain imaging has provided key informations on PAIS-associated neuroinflammation, on long COVID-associated hypometabolism, and even on COVID-induced changes in brain structures

sadly, many patients develop severe fatal outcomes because of overwhelming inflammation known as cytokine storm (248, 249), that leads to ROS-mediated cell death and tissue damage typical of RNA viruses (250)

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These results suggest that the compound induced a parasite-killing mechanism through regulation of the macrophage activation, as was explained in Section 2.3

Both approaches have merit, and many practitioners recommend a combination strategy

Phenolic acids, such as caffeic acid and ferulic acid, are another important class of phenolic compounds