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3), including H-bonds with the backbone of S129 ECD , and hydrophobic interactions with D77 ECD , G78 ECD , W79 ECD , Y131 ECD and W128 ECD , consistent with interactions also formed by Pro32 of sCT

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These effects may potentially provide a new therapeutic solution for stroke with specific beneficial effects on the CNS (i.e., reperfusion, amelioration of neuronal damage leading to recovery in the absence of memory, motor, and coordination deficits, and expression of specific genes in the hippocampus)

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Sirichoat, A