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Innovations such as encapsulation techniques, nano formulations, and diet-based interventions should be explored

Funding Authors work has been funded by Consejo Nacional de Ciencia y Tecnologa (CONACYT 0253804 to AG) and from Instituto Nacional de Cancerologa, MEXICO

For how we grade the evidence behind each of these, see our peptide evidence grades

Aqua (Water) The primary solvent of most skincare products

Gowd, V

Moreover, the ability of polyphenols to penetrate the BBB is compound specific and often suboptimal, necessitating advanced delivery strategies such as nanoformulations or prodrugs to enhance CNS targeting (Ramakrishna et al