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the composition is topically applied to the affected skin areas in a predetermined or as-needed regimen to bring about improvement, it generally being the case that gradual improvement is noted with each successive application

These pathways create a permissive environment for tumor growth, metastasis, and resistance to therapy 29 (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Tran T.Q., Ishak Gabra M.B., Lowman X.H., Yang Y., Reid M.A., Pan M., OConnor T.R., Kong M