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Additionally, untargeted metabolomics revealed that IGF1R drives the activation of lactate dehydrogenase A (LDHA) in glycolysis, further facilitating EMT

The monolayer was wounded with a 1,000-l pipette tip (Watson), washed with media and incubated in growth medium without rh EGF and with 0.25 nM hHGF or 100 nM dimeric macrocycles for 50 h

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* Correspondence: Jie Li [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers