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Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing

This reinforces the central role of the HFD in defining complex-specific incorporation and essential function, in line with observations in budding yeast (37)

doi: 10.1101/2020.12.15.20244160 3 ThompsonPDPanzaGZaleskiATaylorB

Its tertiary amine structure facilitates penetration across the bloodbrain barrier, enabling central nervous system (CNS) effects via interaction with central muscarinic receptors

Wang YJ, Guan Z, Xie LY, Zhao RX, Li YY, Guan ZP & Zhang FG

Mense SM, Zhang L (2006) Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases