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Antagonizing the EP1 receptors or agonizing EP4 may reduce kidney injury associated with growth/apoptosis, inflammation, oxidative stress, and fibrosis and control dysfunction in diabetic patients, thereby reducing the need for kidney replacement therapies (Nasrallah et al., 2016)

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Bhatia, K., Mal, G., Bhar, R., Jyoti, Attri, C., and Seth, A., Int

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While current clinical and anecdotal evidence hasnt shown an increased risk, caution makes sense, especially if you have a history of cancer or concerns about tumors

Open Questions How much iron is required to trigger ferroptosis