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PMID: 24946038

Itoh is also conducting a phase II study (UMIN000030609) to assess the safety of long-term NMN in healthy subjects, the kinetics of NMN and metabolites of NAM, and the effect of daily administration of NMN on glucose metabolism

Patients with MS can present with a variety of neurological dysfunctions, including ataxia, dexterity loss, myoclonus, spasticity, paraparesis or hemiparesis, vision loss and cognitive deficits, depending on the different pathways involved