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However, other observations suggest that the residual CD38 low/- NK population displays a high proliferative potential and functional activity

But even this doesnt always give a clearcut answer on whether there is a B12 deficiency Two secondary tests measure B12 function The secondary tests that measure how well B12 functions in the cells, are called functional tests

Lanier LL

In such cases, your doctor will assess your symptoms and assign you a provocation test such as an insulin tolerance test to confirm the diagnosis

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Doses beyond that threshold produced no additional benefit but increased cost per injection cycle by 300%