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Correlations of C-reactive protein levels and erythrocyte sedimentation rates with endoscopic activity indices in patients with ulcerative colitis

These include: Nausea (most common, especially during dose escalation) Vomiting Diarrhea Constipation Reduced appetite (expected and part of the mechanism) Abdominal discomfort These effects are most pronounced during dose titration and tend to diminish over time as the body adapts