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[DOI] [PubMed] [Google Scholar] 47.Wake R, Miyaoka T, Tsuchie K, Kawakami K, Nishida A, Inagaki T, Horiguchi J

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Effect of a novel IL-2 cytokine immune agonist (NKTR-214) on proliferating CD8+T cells and PD-1 expression on immune cells in the tumor microenvironment in patients with prior checkpoint therapy

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Similarly, histamine production from gut microbiota appears to provide anti-inflammatory effects by suppressing TNF- [186]