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10.1016/j.eclinm.2024.102529 EClinicalMedicine 105 YangX.-E.ZhangS.-J.LiuY.YaoS.-Y.ZhangS.-X.LiuX.-M.et al (2025)

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NICE obesity guidance (CG189) directs individuals towards structured lifestyle interventions, behavioural support, and, where appropriate, pharmacological or surgical options No authorised health claims for L-carnitine and weight loss or fat metabolism exist on the GB Nutrition and Health Claims Register In summary, while L-carnitine pills are not harmful for most healthy adults when taken at recommended doses, the evidence supporting their use specifically for weight loss remains insufficiently robust to justify clinical endorsement

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