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doi: 10.3389/fchem.2019.00558 Received 31 May 2019 Accepted 22 July 2019 Published 13 August 2019 Volume 7 - 2019 Edited by Chiung-Wen Hu, Chung Shan Medical University, Taiwan Reviewed by Qingping Wang, Sanofi, United States

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Table of Contents What Is Retatrutide and Its Role in Weight Loss Treatment Understanding Retatrutide Reconstitution: Important Safety Information Reconstitution Calculators: Why They Are Not Appropriate for Patient Use Dosing Considerations and MHRA Safety Guidance Risks of Incorrect Reconstitution and When to Seek Advice Accessing Weight Loss Medicines Safely Through UK Healthcare Scientific References Frequently Asked Questions What Is Retatrutide and Its Role in Weight Loss Treatment Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, and glucagon) not yet licensed by the MHRA or EMA, meaning it cannot legally be prescribed or supplied as a medicine in the UK outside approved clinical trials

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