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Clinical situations with elevated procalcitonin levels without bacterial infection Blood PCT levels can be elevated in patients with severe systemic inflammation from non-bacterial causes, including respiratory failure caused by severe viral respiratory infections [13, 14], malaria, bowel wall ischemia, vasculitis or cancer [3]

Kapoor, Pooja Middha

Studies suggest this inflammatory process may be connected with the development of neurological illnesses such as depression, fibromyalgia, ME/CFS and Parkinson's disease

Mechanistic studies in humans are challenging, but neuroimaging studies and in vitro human-banked tissue studies of specific brain regions could be instrumental in demonstrating translational value

Statistical analyzes Statistical analyzes were performed using GraphPad Prism software, version 6.0 (GraphPad, San Diego)

Theoretical concerns include off-target cell death, immune burden from clearing many cells at once, impaired wound healing, and injection-site irritation