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Dp71f and Dp71d isoforms bind in vitro to the nuclear envelope proteins lamin B1 and emerin Given that both Dp71d and Dp71f utilize the importin 2/1 system to enter the nucleus, there may be a mechanism that favors nuclear retention of Dp71d but not Dp71f

Beyond-use dating principles from the United States Pharmacopeia General Chapter treat preservative-containing solutions as having longer safe in-use windows than preservative-free ones