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We are pleased to have been involved in producing the new guideline, and we will be participating in producing a new Guideline on the Treatment of Cobalamin and Folate Disorders later this year.

Acknowledgements This work was supported by Science and Engineering Research Board (SERB) project no: SB/YS/LS-194/2013

This study expands the genotypic and phenotypic spectrum of metabolic neurodevelopmental disorders and highlights the importance of fatty acid transport proteins in mitochondrial health and brain development