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While FOXO4-DIR carries substantial promise as a senolytic agent against cellular senescence, its safety profile remains largely uncharted

PMID 11169096

overexpressed miR-340-5p in the myocardium by direct myocardial injection of AVV-9 containing miR-340-5p precursor, which targeted inhibition of MyD88 and thus restored declining GSH levels, alleviated insult of cardiac function and oxidative injury induced by sepsis in the hearts of mice [253]