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The systemic effects of growth hormone secretagogues differ substantially from the targeted local effects of topically applied AHK-Cu

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By integrating endocrine, metabolic, and exosomal signaling across multiple organ and brain axes, physical activity reconfigures systemic iron, lipid, and antioxidant homeostasis to suppress ferroptosis initiation and amplification in the central nervous system (Majernikova et al., 2024

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