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Divergent behaviour of oxidative stress markers 8-hydroxydeoxyguanosine (8-OHdG) and 4-hydroxy-2-nonenal (HNE) in breast carcinogenesis

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The flow rate was set at 5 l/min and the run was carried out using the following solvents: solvent A 98% water and 2% acetonitrile containing 0.1% formic acid (v/v), and solvent B 98% acetonitrile and 2% water containing 0.1% formic acid (v/v)

The area under the curve (AUC) values did not change significantly (Table 6)