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It contributes to fungal virulence [141] and dissemination [142], as well as the inhibition of phagocytosis [131]

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When buoyed by allergens, infection factors and toxins, IL-25, IL-33 and thymic stromal lymphatic hormone to be released in epithelial cells and Th2 cells and ILCs produce and secrete, IL-4, IL-5, IL-9 and IL-13 type 2 cytokines, thus having type 2 reaction (103, 104) ( Figure 4 )